beta 2 Adrenergic Receptor 抗体 (AA 302-413)
Quick Overview for beta 2 Adrenergic Receptor 抗体 (AA 302-413) (ABIN5542567)
抗原
See all beta 2 Adrenergic Receptor (ADRB2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 302-413
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原理
- ADRB2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human ADRB2 (AA: 302-413) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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别名
- ADRB2
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背景
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This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
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分子量
- 46.5 kDa
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基因ID
- 154
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UniProt
- P07550
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途径
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
抗原
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