TCL1A 抗体 (AA 10-104)
Quick Overview for TCL1A 抗体 (AA 10-104) (ABIN5542543)
抗原
See all TCL1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 10-104
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原理
- TCL1A Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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别名
- TCL1A
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背景
- Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).
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分子量
- 13.5 kDa
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基因ID
- 8115
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UniProt
- P56279
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途径
- Stem Cell Maintenance
抗原
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