RAP1GAP 抗体 (AA 412-660)
Quick Overview for RAP1GAP 抗体 (AA 412-660) (ABIN5542476)
抗原
See all RAP1GAP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 412-660
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原理
- RAP1GAP Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human RAP1GAP (AA: 412-660) expressed in E. Coli.
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亚型
- IgG2b
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anti-RAP1 GTPase Activating Protein (RAP1GAP) (Internal Region) antibody
RAP1GAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (AA 412-678) antibodyRAP1GAP 适用: 人 宿主: 小鼠 Monoclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (C-Term) antibodyRAP1GAP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (C-Term) antibodyRAP1GAP 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) antibodyRAP1GAP 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (AA 451-550) antibodyRAP1GAP 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (C-Term) antibodyRAP1GAP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (AA 105-128) antibodyRAP1GAP 适用: 人 WB 宿主: 兔 Polyclonal RB53561 unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (C-Term) antibodyRAP1GAP 适用: 人, 小鼠, Cow, 豚鼠, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (AA 1-663) antibodyRAP1GAP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F7 unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))
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别名
- RAP1GAP
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背景
- This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.
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分子量
- 73.4 kDa
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UniProt
- P47736
抗原
-
