TERT 抗体 (AA 1029-1132)
Quick Overview for TERT 抗体 (AA 1029-1132) (ABIN5542472)
抗原
See all TERT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1029-1132
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原理
- TERT Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human TERT (AA: 1029-1132) expressed in E. Coli.
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亚型
- IgG1
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anti-Telomerase Reverse Transcriptase (TERT) (C-Term) antibody
TERT 适用: 人 WB, ELISA, IHC, IP, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (C-Term) antibodyTERT 适用: 人 WB, ELISA, IHC, IP, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 601-750) antibodyTERT 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 627-656) antibodyTERT 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 597-611) antibodyVerified TERT 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) antibodyTERT 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 1268-1341) antibodyTERT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (pTyr707) antibodyTERT 适用: 人 IF, DB 宿主: 兔 Polyclonal RB16840 unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (pTyr707) antibodyTERT 适用: 人 ELISA, IF, DB 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 1104-1132) antibodyTERT 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TERT (Telomerase Reverse Transcriptase (TERT))
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别名
- TERT
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背景
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Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified, the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.
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分子量
- 127 kDa
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UniProt
- O14746
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途径
- Telomere Maintenance
抗原
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