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LDLR 抗体 (AA 22-150)

This anti-LDLR antibody is a 小鼠 单克隆 antibody detecting LDLR in IHC, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN5542334
发货至: 中国

Quick Overview for LDLR 抗体 (AA 22-150) (ABIN5542334)

抗原

See all LDLR 抗体
LDLR (Low Density Lipoprotein Receptor (LDLR))

适用

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  • 2
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  • 1

宿主

  • 81
  • 14
  • 5
小鼠

克隆类型

  • 77
  • 22
  • 1
单克隆

标记

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  • 1
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This LDLR antibody is un-conjugated

应用范围

  • 71
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  • 11
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  • 2
  • 2
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  • 1
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  • 1
Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

克隆位点

1B10H10
  • 抗原表位

    • 16
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-150

    原理

    LDLR Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human LDLR (AA: 22-150) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    LDLR (Low Density Lipoprotein Receptor (LDLR))

    别名

    LDLR

    背景

    The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.r

    分子量

    95.4 kDa

    基因ID

    3949

    UniProt

    P01130

    途径

    Hepatitis C, Lipid Metabolism
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