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BIN1 抗体 (AA 189-398)

This anti-BIN1 antibody is a 小鼠 单克隆 antibody detecting BIN1 in WB, ELISA 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN5542281
发货至: 中国

Quick Overview for BIN1 抗体 (AA 189-398) (ABIN5542281)

抗原

See all BIN1 抗体
BIN1 (Bridging Integrator 1 (BIN1))

适用

  • 53
  • 27
  • 19
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 38
  • 18
  • 1
小鼠

克隆类型

  • 34
  • 23
单克隆

标记

  • 48
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BIN1 antibody is un-conjugated

应用范围

  • 45
  • 28
  • 18
  • 16
  • 15
  • 13
  • 8
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

3B6A4
  • 抗原表位

    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 189-398

    原理

    BIN1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human BIN1 (AA: 189-398) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    BIN1 (Bridging Integrator 1 (BIN1))

    别名

    BIN1

    背景

    This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

    分子量

    64.7 kDa

    基因ID

    274

    UniProt

    O00499
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