FH 抗体 (AA 44-510)
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北京 101111
Quick Overview for FH 抗体 (AA 44-510) (ABIN5542251)
抗原
See all FH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 44-510
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纯化方法
- Protein-A affinity chromatography
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免疫原
- Recombinant human Fumarase (44-510aa) purified from E. coli.
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亚型
- IgG2a
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应用备注
- The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- FH (Fumarate Hydratase (FH))
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别名
- fumarase
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背景
- Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-termil extended mitochondrial form. The N-termil extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor.
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UniProt
- P07954
抗原
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