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PRPS1 抗体 (AA 1-318)

This anti-PRPS1 antibody is a 小鼠 单克隆 antibody detecting PRPS1 in WB, IF, ICC 和 EIA. Suitable for 人.
产品编号 ABIN5542153
发货至: 中国

Quick Overview for PRPS1 抗体 (AA 1-318) (ABIN5542153)

抗原

See all PRPS1 抗体
PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

适用

  • 9
  • 2
  • 1

宿主

  • 6
  • 3
小鼠

克隆类型

  • 7
  • 2
单克隆

标记

  • 9
This PRPS1 antibody is un-conjugated

应用范围

  • 9
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)

克隆位点

AT1E11
  • 抗原表位

    • 4
    • 2
    • 1
    AA 1-318

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Recombinant human PRPS1 (1-318aa) purified from E. coli

    亚型

    IgG2a
  • 应用备注

    The antibody has been tested by ELISA, Western blot analysis and Immunofluorescence / Immnunocytochemistry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

    别名

    prps1

    背景

    PRPS1 is an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. A mutation in PRPS1 may result in PRPS superactivity, a disease characterized by gout and the overproduction of purine nucleotides, uric acid and PRPP. PRPS1 mutations can also lead to a reduction in PRPS1 activity resulting in ARTS syndrome or CMTX5 (Charcot-Marie-Tooth disease X-linked recessive type 5).

    UniProt

    P60891

    途径

    Ribonucleoside Biosynthetic Process
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