MMP17 抗体
Our Local Distributor
北京 101111
Quick Overview for MMP17 抗体 (ABIN5542064)
抗原
See all MMP17 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody recognizes Human MMP-17 by direct ELISA.
-
纯化方法
- Protein G Chromatography
-
免疫原
- Recombinant Human MMP-17
-
亚型
- IgG2
-
-
-
-
应用备注
- ELISA: 1/1000-1/2000. Neutralization.
-
限制
- 仅限研究用
-
-
-
缓冲液
- Sterile PBS
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
-
有效期
- 12 months
-
-
- MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))
-
别名
- mmp-17
-
背景
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage and is known to be expressed in brain, leukocytes, colon, ovary testis and breast cancer as well as in many transformed and non-transformed cell types. The protein exists in two isoforms: a GPI-anchored form and a second secreted form.
-
UniProt
- Q9ULZ9
抗原
-