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CD81 抗体

The 大鼠 单克隆 anti-CD81 antibody is suitable to detect CD81 in samples from 人. It has been validated for FACS 和 EIA.
产品编号 ABIN5541933
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD81 抗体 (ABIN5541933)

抗原

See all CD81 抗体
CD81

适用

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大鼠

克隆类型

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单克隆

标记

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This CD81 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

克隆位点

QV-6A8-S3
  • 特异性

    Recognizes Human CD81. Other species not tested. Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    cDNA encoding Human CD81

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry: 1.2 μg/10 6 cells. ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.2

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD81

    别名

    cd81,tapa1

    背景

    CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL) (1). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins (2,3). CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry (4).

    UniProt

    P60033

    途径

    Inositol Metabolic Process, Hepatitis C
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