GNRH1 抗体 (AA 11-60)
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Quick Overview for GNRH1 抗体 (AA 11-60) (ABIN5541891)
抗原
See all GNRH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 11-60
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特异性
- This antibody detects endogenous levels of GnRH 1 protein.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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免疫原
- Synthetic peptide corresponding to amino acids 11-60 of Human GnRH I.
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应用备注
- Western blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 95 % by SDS-PAGE) Aff - Purified
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))
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别名
- gnrh1,progonadoliberin-1
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背景
- GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the median eminence. GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary. In addition to hypothalamic GnRH (GnRH I), a second GnRH form (GnRH II) functions primarily in the midbrain. GnRH is xpressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells. Unlike GnRH I, GnRH II is highly expressed outside the brain, particularly in the kidney, bone marrow and prostate, suggesting that it may have multiple functions. GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins.
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UniProt
- P01148
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途径
- Hormone Activity
抗原
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