PRSS1 抗体 (HRP)
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北京 101111
Quick Overview for PRSS1 抗体 (HRP) (ABIN5541698)
抗原
See all PRSS1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects bovine trypsin. Cross reactivity from other sources is unknown. Immunoelectrophoresis give a single precipitin arc against anti-peroxidase, anti-rabbit serum as well as purified and partially purified trypsin [bovine pancreas].
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纯化方法
- Multi-step process including delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer
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免疫原
- Trypsin from bovine pancreas
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应用备注
- ELISA : 1/14,000. Western blot: 1/1,000-1/5,000. Immunohistochemistry : Paraffin (FFPE) or Frozen sections 1/100 suggested to begin.
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限制
- 仅限研究用
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))
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别名
- trypsin-1,prss1
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背景
- Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screen for and diagnose Cystic Fibrosis.
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UniProt
- P00760
抗原
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