Rituximab 抗体 (HRP)
This anti-Rituximab antibody is a 大鼠 单克隆 antibody detecting Rituximab in EIA. Suitable for .
Quick Overview for Rituximab 抗体 (HRP) (ABIN5541687)
抗原
Rituximab
适用
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宿主
大鼠
克隆类型
单克隆
标记
This Rituximab antibody is conjugated to HRP
应用范围
Enzyme Immunoassay (EIA)
克隆位点
MB2 A4
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特异性
- This antibody specifically recognises the idiotypic determinants expressed by the Rituximab humanised monoclonal antibody. This antibody does not recognise other CD20 antibodies. It has been used to detect Rituximab bound to the surface of the Raji B cell line, however detection of Rituximab bound 'in vivo' to B-CLL cells has not been demonstrated. It is possible that complement deposition on Rituximab opsonised cells inhibits binding of the anti-Rituximab antibody to cell bound Rituximab (3). Clone MB2A4 has been used in ELISA assays to monitor the levels of rituximab in patient serum following therapy (4,5).
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- F(ab)2 fragment of Rituximab
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亚型
- IgG2a
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anti-Rituximab antibody
适用: 小鼠 FACS, EIA 宿主: 大鼠 Monoclonal MB2 A4 unconjugated
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应用备注
- ELISA: 1/20000-1/20000.
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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有效期
- 12 months
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- Rituximab
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物质类
- Antibody
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背景
- Rituximab is a therapeutic reagent directed against the human CD20 cell surface antigen.
抗原
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