ACOX1 抗体
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北京 101111
Quick Overview for ACOX1 抗体 (ABIN5541563)
抗原
See all ACOX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes Human ACOX1. Other species not tested.
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纯化方法
- Protein G Chromatography, followed by dialysis against PBS
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免疫原
- ACOX1 recombinant protein.
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亚型
- IgG1
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anti-Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) (AA 1-270) antibody
ACOX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) (AA 210-409) antibodyACOX1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) (AA 113-273) antibodyACOX1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) antibodyACOX1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C1 unconjugated
anti-Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) antibodyACOX1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) (AA 1-660) antibodyACOX1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) antibodyACOX1 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) (AA 1-660) antibodyACOX1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) (AA 1-660) antibodyACOX1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Acyl-CoA Oxidase 1, Palmitoyl (ACOX1) (AA 629-659), (C-Term) antibodyACOX1 适用: 人 WB 宿主: 兔 Polyclonal RB04651-04652 unconjugated
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应用备注
- Western blot: 1/100-1/500. Immunofluorescence: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/10-1/50.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS Preservatives: 0.09 % (W/V) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))
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别名
- acox1
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背景
- ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Function: Catalyzes the desaturation of acyl-CoAs to 2-trans- enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy- palmitoyl-CoA and is 25 % more active against 1,16-hexadecanodioyl- CoA. Cellular Location: Peroxisome. Tissue Location: Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.
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UniProt
- Q15067
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途径
- Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process
抗原
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