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LARGE 抗体 (AA 35-142) (PE)

This anti-LARGE antibody is a 小鼠 单克隆 antibody detecting LARGE in FACS. Suitable for 人.
产品编号 ABIN5541531
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LARGE 抗体 (AA 35-142) (PE) (ABIN5541531)

抗原

See all LARGE 抗体
LARGE (Like-Glycosyltransferase (LARGE))

适用

  • 8
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2

宿主

  • 5
  • 2
  • 1
小鼠

克隆类型

  • 7
  • 1
单克隆

标记

  • 8
This LARGE antibody is conjugated to PE

应用范围

  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

LARGE-02
  • 抗原表位

    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-142

    特异性

    Thisa ntibody recognizes human LARGE1, a glycosyltransferase localizing mainly to the Golgi apparatus. Crossreactivity with LARGE2 was not determined.

    免疫原

    Recombinant fragment of human LARGE1 (amino acids 35-142)

    亚型

    IgG2b
  • 应用备注

    Flow cytometry.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    LARGE (Like-Glycosyltransferase (LARGE))

    别名

    large

    背景

    LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer, as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.

    UniProt

    O95461
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