LARGE 抗体 (AA 35-142)
Quick Overview for LARGE 抗体 (AA 35-142) (ABIN5541530)
抗原
See all LARGE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 35-142
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特异性
- This antibody recognizes human LARGE1, a glycosyltransferase localizing mainly to the Golgi apparatus. Crossreactivity with LARGE2 was not determined.
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纯化方法
- Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
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免疫原
- Recombinant fragment of human LARGE1 (amino acids 35-142)
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亚型
- IgG2b
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anti-Like-Glycosyltransferase (LARGE) (AA 25-178) antibody
LARGE 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Like-Glycosyltransferase (LARGE) (AA 365-398) antibodyLARGE 适用: 人 WB 宿主: 兔 Polyclonal RB55257 unconjugated
anti-Like-Glycosyltransferase (LARGE) (AA 421-433) antibodyVerified LARGE 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Like-Glycosyltransferase (LARGE) (AA 683-732) antibodyLARGE 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 大鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Like-Glycosyltransferase (LARGE) (Middle Region) antibodyLARGE 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 大鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry. Western blot.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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有效期
- 12 months
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- LARGE (Like-Glycosyltransferase (LARGE))
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别名
- large
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背景
- LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer, as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.
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UniProt
- O95461
抗原
-
