This antibody recognizes Helios, a transcription factor expressed in some hematopoietic stem cells, and at high levels in thymic-derived regulatory T cells.
免疫原
Peptide coresponding to the amino acids 51-107 of Helios
Flow cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10 6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
限制
仅限研究用
状态
Liquid
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.
有效期
12 months
抗原
IKZF2
(IKAROS Family Zinc Finger 2 (IKZF2))
别名
znfn1a2 (ikzf2, helios)
背景
Helios, also known as IKZF2 (Ikaros family zinc finger protein 2) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Ikaros. Helios forms homo- and heterodimers with these proteins and is thought to function predominantly in early hematopoietic development. Expression of Helios, Aiolos and Ikaros is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Helios is expressed at early stages of thymocyte development. In mature T cells, Helios has been strongly associated with Treg cells.