PAK6 抗体 (pSer560, pSer602)
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Quick Overview for PAK6 抗体 (pSer560, pSer602) (ABIN5541295)
抗原
See all PAK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer560, pSer602
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特异性
- The antibody detects endogenous levels of PAK5/6 only when phosphorylated at serine 602/560.
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纯化方法
- Affinity chromatography using epitope-specific peptide
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免疫原
- Peptide sequence around phosphorylation site of Serine 602/560(R-K-S(p)-L-V) derived from Human PAK5/6 (KLH-conjugated)
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应用备注
- Western blot: 1:500~1:1000.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- PAK6 (P21-Activated Kinase 6 (PAK6))
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别名
- pak6
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背景
- This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development.
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UniProt
- Q9NQU5
抗原
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