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PAK6 抗体 (pSer560, pSer602)

This anti-PAK6 antibody is a 兔 多克隆 antibody detecting PAK6 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN5541295
发货至: 中国

Quick Overview for PAK6 抗体 (pSer560, pSer602) (ABIN5541295)

抗原

See all PAK6 抗体
PAK6 (P21-Activated Kinase 6 (PAK6))

适用

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人, 小鼠

宿主

  • 78

克隆类型

  • 77
多克隆

标记

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This PAK6 antibody is un-conjugated

应用范围

  • 53
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Western Blotting (WB)
  • 抗原表位

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    pSer560, pSer602

    特异性

    The antibody detects endogenous levels of PAK5/6 only when phosphorylated at serine 602/560.

    纯化方法

    Affinity chromatography using epitope-specific peptide

    免疫原

    Peptide sequence around phosphorylation site of Serine 602/560(R-K-S(p)-L-V) derived from Human PAK5/6 (KLH-conjugated)
  • 应用备注

    Western blot: 1:500~1:1000.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    PAK6 (P21-Activated Kinase 6 (PAK6))

    别名

    pak6

    背景

    This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development.

    UniProt

    Q9NQU5
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