FUBP1 抗体 (AA 279-448)
Our Local Distributor
北京 101111
Quick Overview for FUBP1 抗体 (AA 279-448) (ABIN5541255)
抗原
See all FUBP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 279-448
-
纯化方法
- Protein-A affinity chromatography
-
免疫原
- Recombinant human FUBP1 (279-448aa) purified from E.coli.
-
亚型
- IgG2b
-
-
-
-
应用备注
- The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
-
有效期
- 12 months
-
-
- FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))
-
别名
- fubp1
-
背景
- FUBP1 is a transcriptiol regulator and fulfills an important function in the precise control of c-myc transcription. The c-Myc protein is a transcription factor which regulates the transcription of many different target genes that play a role in proliferation, cell cycle progression, differentiation, apoptosis and cell metabolism. Consequently, FUBP1 is also involved in the regulation of proliferation and differentiation, as confirmed by different experimental approaches. Knockdown of FUBP1 or expression of a domint-negative FUBP1 (D-binding domain lacking effector activity) led to proliferation arrest in U2OS and Saos-2 osteosarcoma cells due to reduced c-myc expression.
-
UniProt
- Q96AE4
抗原
-