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FUBP1 抗体 (AA 279-448)

This anti-FUBP1 antibody is a 小鼠 单克隆 antibody detecting FUBP1 in WB, IF, ICC 和 EIA. Suitable for 人.
产品编号 ABIN5541255
发货至: 中国

Quick Overview for FUBP1 抗体 (AA 279-448) (ABIN5541255)

抗原

See all FUBP1 抗体
FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

适用

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宿主

  • 41
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小鼠

克隆类型

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单克隆

标记

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This FUBP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)

克隆位点

AT14F5
  • 抗原表位

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    AA 279-448

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Recombinant human FUBP1 (279-448aa) purified from E.coli.

    亚型

    IgG2b
  • 应用备注

    The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

    别名

    fubp1

    背景

    FUBP1 is a transcriptiol regulator and fulfills an important function in the precise control of c-myc transcription. The c-Myc protein is a transcription factor which regulates the transcription of many different target genes that play a role in proliferation, cell cycle progression, differentiation, apoptosis and cell metabolism. Consequently, FUBP1 is also involved in the regulation of proliferation and differentiation, as confirmed by different experimental approaches. Knockdown of FUBP1 or expression of a domint-negative FUBP1 (D-binding domain lacking effector activity) led to proliferation arrest in U2OS and Saos-2 osteosarcoma cells due to reduced c-myc expression.

    UniProt

    Q96AE4
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