EGFL7 抗体 (C-Term)
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Quick Overview for EGFL7 抗体 (C-Term) (ABIN5541243)
抗原
See all EGFL7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 178-273, C-Term
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特异性
- This antibody recognizes VE-Statin / EGFL7 at C-term.
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纯化方法
- Protein A chromatography
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免疫原
- Highly pure recombinant human EGFL7 (Pro178-Ser273) C-terminus derived from insect cells
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亚型
- IgG
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anti-EGF-Like-Domain, Multiple 7 (EGFL7) (AA 1-273) antibody
EGFL7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-EGF-Like-Domain, Multiple 7 (EGFL7) (AA 22-275) antibodyEGFL7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-EGF-Like-Domain, Multiple 7 (EGFL7) (AA 24-273) antibodyEGFL7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-EGF-Like-Domain, Multiple 7 (EGFL7) (AA 30-80) antibodyEGFL7 适用: 人, 小鼠, 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-EGF-Like-Domain, Multiple 7 (EGFL7) (AA 24-273) antibodyEGFL7 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-EGF-Like-Domain, Multiple 7 (EGFL7) (AA 24-100) antibodyEGFL7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-EGF-Like-Domain, Multiple 7 (EGFL7) (AA 73-198) antibodyEGFL7 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EGF-Like-Domain, Multiple 7 (EGFL7) (Internal Region) antibodyVerified EGFL7 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-EGF-Like-Domain, Multiple 7 (EGFL7) (AA 24-273) antibodyEGFL7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-EGF-Like-Domain, Multiple 7 (EGFL7) (AA 1-273) antibodyEGFL7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Western blot: 2-5 μg/mL. Immunohistochemistry on Frozen sections. Immnunocytochemistry. Immunoprecipitation.
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限制
- 仅限研究用
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缓冲液
- PBS
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储存条件
- 4 °C,-20 °C
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储存方法
- Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))
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别名
- egfl7
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背景
- EGFL7 (EGF-like domain-containing protein 7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro. EGFL7 (VE-Statin) is an ~ 30 kDa secreted protein that contains an Emilin-like (EMI) domain (a multimerization motif), and two epidermal growth factor (EGF) domains, one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may self-assemble like extracellular matrix (ECM) proteins and, thus, could incorporate into ECM. EGFL7 has been reported to stimulate cell adhesion as well as motility in a manner similar to ECM proteins. EGFL7 has been shown to be primarily expressed by developing ECs but also by primordial germ cells and some central nervous system neurons. Interestingly, EGFL7 expression markedly decreases in ECs in postnatal life, but can be strongly up-regulated after various tissue injuries that lead to increased angiogenic responses.
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UniProt
- Q9UHF1
抗原
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