CEACAM20 抗体
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北京 101111
Quick Overview for CEACAM20 抗体 (ABIN5541205)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes CEACAM20
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Genetic immunisation with cDNA encoding Human CEACAM20.
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亚型
- IgG1
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应用备注
- Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. ELISA (capture): With clone HD-6G4-A5 as detection antibody. Flow cytometry: 1.2 μg/10e6 cells. Immunofluorescence: 1 μg/10e6 cells.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered saline, pH 7.2
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 (CEACAM20))
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别名
- ceacam20
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背景
- CEA-related cell adhesion molecule 20 (CEACAM20) belongs to the carcinoembryonic antigen (CEA) gene family (1). It encodes a putative glycoprotein which is membrane-bound via a transmembrane domain. The CEACAM20 protein contains a single N domain followed by 4 immunoglobulin-like A (A1, A2) and B (B1, B2) domains. Expression of CEACAM20 can be found in tissues of prostate, testis, duodenum and small intestine with highest expression in prostate. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. High expression of CEACAM20 in tissue of prostate carcinoma and in prostate carcinoma cell lines suggest that CEACAM20 can be used as a tumor marker.
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UniProt
- Q6UY09
抗原
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