CEACAM7 抗体
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北京 101111
Quick Overview for CEACAM7 抗体 (ABIN5541193)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes CEACAM7.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- CEACAM7/Fc fusion protein
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亚型
- IgG1
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) (AA 147-231) antibody
CEACAM7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) antibodyCEACAM7 适用: 人 WB, ELISA, FACS, IHC (fro), cELISA 宿主: 小鼠 Monoclonal BAC2 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) (AA 112-140) antibodyCEACAM7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB35958 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) (C-Term) antibodyCEACAM7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) (N-Term) antibodyCEACAM7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) (Internal Region) antibodyCEACAM7 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) (AA 36-242) antibodyCEACAM7 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) (AA 36-242) antibodyCEACAM7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) (AA 142-191) antibodyCEACAM7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) (AA 61-110) antibodyCEACAM7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200. Flow cytometry: 1.2 μg/10 6 cells.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered saline, pH 7.2 without preservatives
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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: "The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 7, pp. 1697-707, (2009) (PubMed).
: "Interleukin-4 suppresses the cytotoxic potential of in vitro generated, adaptive regulatory CD4 T cells by down-regulation of granzyme B." in: Immunology, Vol. 127, Issue 3, pp. 338-44, (2009) (PubMed).
: "Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow." in: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15647-55, (2008) (PubMed).
: "Lymphatic reprogramming of microvascular endothelial cells by CEA-related cell adhesion molecule-1 via interaction with VEGFR-3 and Prox1." in: Blood, Vol. 110, Issue 13, pp. 4223-33, (2007) (PubMed).
: "Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence." in: Scandinavian journal of immunology, Vol. 58, Issue 6, pp. 628-41, (2003) (PubMed).
: "Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas." in: The American journal of pathology, Vol. 156, Issue 2, pp. 595-605, (2000) (PubMed).
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- CEACAM7 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7))
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别名
- ceacam7
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背景
- CEA-related cell adhesion molecule 7 (CEACAM7, CGM2) belongs to the carcinoembryonic antigen (CEA) family (1). It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts (2). CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon (2). Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constant-like A domain.
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UniProt
- Q14002
抗原
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