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ASF1B 抗体 (AA 1-202)

The 小鼠 单克隆 anti-ASF1B antibody is suitable to detect ASF1B in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN5541030
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ASF1B 抗体 (AA 1-202) (ABIN5541030)

抗原

See all ASF1B 抗体
ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))

适用

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宿主

  • 16
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小鼠

克隆类型

  • 16
  • 5
单克隆

标记

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This ASF1B antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

AT1D4
  • 抗原表位

    • 10
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    AA 1-202

    特异性

    Recognizes Human ASF1B. Other species not tested.

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Recombinant human ASF1B (1-202aa) purified from E. coli.

    亚型

    IgG2b
  • 应用备注

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))

    别名

    asf1b

    背景

    ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. Delivering histone H3/H4 dimers to CAF-1 or HIRA histone deposition complexes to facilitate replication-coupled and replication-independent nucleosome assembly on DNA. Both ASF1A and ASF1B are phosphorylated in S phase by the Tousled-like kinases TLK1 and TLK2, and are dephosphorylated when TLK1 and TLK2 are inactivated by Chk1 kinase in response to replicative stress.

    UniProt

    Q9NVP2

    途径

    Regulation of Cell Size
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