ASF1B 抗体 (AA 1-202)
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北京 101111
Quick Overview for ASF1B 抗体 (AA 1-202) (ABIN5541030)
抗原
See all ASF1B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-202
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特异性
- Recognizes Human ASF1B. Other species not tested.
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纯化方法
- Protein-A affinity chromatography
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免疫原
- Recombinant human ASF1B (1-202aa) purified from E. coli.
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亚型
- IgG2b
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应用备注
- The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))
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别名
- asf1b
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背景
- ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. Delivering histone H3/H4 dimers to CAF-1 or HIRA histone deposition complexes to facilitate replication-coupled and replication-independent nucleosome assembly on DNA. Both ASF1A and ASF1B are phosphorylated in S phase by the Tousled-like kinases TLK1 and TLK2, and are dephosphorylated when TLK1 and TLK2 are inactivated by Chk1 kinase in response to replicative stress.
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UniProt
- Q9NVP2
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途径
- Regulation of Cell Size
抗原
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