CDNF 抗体
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北京 101111
Quick Overview for CDNF 抗体 (ABIN5540985)
抗原
See all CDNF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes Human and Mouse CDNF. Other species not tested.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Recombinant Human CDNF produced using CHO-based. Antigen is purified from cell culture supernatant.
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亚型
- IgG1
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应用备注
- ELISA: 1/5000-1/10000. Western Blot: 1/1000-1/4000. Immunofluorescence: 1/100-1/3000.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.4 Preservatives: 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store (in aliquots) at -20°C to -80°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
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别名
- cdnf
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背景
- CDNF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007 Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson's disease. When administered after 6-OHDA or MPTP -lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
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UniProt
- Q49AH0
抗原
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