CBX1 抗体
Quick Overview for CBX1 抗体 (ABIN5540983)
抗原
See all CBX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects HP1β.
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纯化方法
- Purified
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免疫原
- Recombinant mouse HP1beta
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亚型
- IgG1
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anti-Chromobox Homolog 1 (CBX1) (AA 1-185) antibody
CBX1 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4D7B8 unconjugated
anti-Chromobox Homolog 1 (CBX1) (Center) antibodyCBX1 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) (AA 2-99) antibodyCBX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-Chromobox Homolog 1 (CBX1) (Internal Region) antibodyVerified CBX1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) (AA 1-185) antibodyCBX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) (AA 128-155), (C-Term) antibodyCBX1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23535 unconjugated
anti-Chromobox Homolog 1 (CBX1) (N-Term) antibodyCBX1 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 兔, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) (AA 176-185) antibodyCBX1 适用: 人, Hamster WB, IF, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) antibodyCBX1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) antibodyCBX1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry on paraffin sections: 4 μg/mL (1:50). Microwave pretreatment in citrate buffer is recommended for antigen retrieval. Suggested Positive control: Human / Swine brain cortex.
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限制
- 仅限研究用
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缓冲液
- Buffer System: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.01 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- CBX1 (Chromobox Homolog 1 (CBX1))
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别名
- cbx1
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背景
- Heterochromatin Protein 1 (HP1) (Chromobox Homolog, CBX) includes three isoforms in mammals, designated α, β, and γ. HP1 proteins are approximately 25 kDa in size. They are highly conserved adapter proteins with important regulatory functions in the cell nucleus. These functions include notably gene silencing by heterochromatin formation. HP1 proteins are fundamental units of heterochromatin packaging that are enriched at the centromeres and telomeres of nearly all Eukaryotic chromosomes. HP1 β and γ also localize to euchromatic sites in the genome. Members of the HP1 family are characterized by an N-terminal chromodomain and a C- terminal chromoshadow domain, separated by a Hinge region. Chromodomain and chromoshadow domain establish secondary interactions with a large number of other proteins. HP1 proteins are subject to multiple types of post - translational modifications, including phosphorylation, acetylation, methylation, ubiquitination and sumoylation, suggesting multiple means of regulation.
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UniProt
- P83916
抗原
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