TERT 抗体 (AA 627-656)
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Quick Overview for TERT 抗体 (AA 627-656) (ABIN5540961)
抗原
See all TERT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 627-656
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特异性
- This antibody detects Human TERT at center. Other species not tested.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- KLH conjugated synthetic peptide selected from the Center region of Human TERT.
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应用备注
- Immunofluorescence: 1/10-1/50. Western blot: 1/1000, Flow Cytometry: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/100.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS Preservatives: 0.09 % (W/V) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- TERT (Telomerase Reverse Transcriptase (TERT))
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别名
- tert
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背景
- Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.
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UniProt
- O14746
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途径
- Telomere Maintenance
抗原
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