TERT
适用: 人
ELISA, IF, DB
宿主: 兔
Polyclonal
unconjugated
应用备注
Immunofluorescence: 1/10-1/50. Western blot: 1/1000, Flow Cytometry: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/100.
限制
仅限研究用
状态
Liquid
缓冲液
PBS Preservatives: 0.09 % (W/V) Sodium Azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
有效期
12 months
抗原
TERT
(Telomerase Reverse Transcriptase (TERT))
别名
tert
背景
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.