MRGPRX2 抗体
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北京 101111
Quick Overview for MRGPRX2 抗体 (ABIN5540874)
抗原
See all MRGPRX2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects Human MRGPRX2 (GPCRx11).
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纯化方法
- Protein G
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免疫原
- DNA vaccine
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亚型
- IgG2b
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应用备注
- Immunohistochemistry on paraffin sections: 1 μg/mL (1/200). Positive control: Human placenta.
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限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
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别名
- mrgprx2
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背景
- MRGPRX2 or cortistatin receptor is a 330 amino acid protein that belongs to the G - protein coupled receptor 1 family. Mas - related G - protein - coupled receptors (Mrgprs) represent a large family of orphan receptors specifically expressed in small - diameter nociceptive primary sensory neurons. Physiological functions include mediation of itch or regulat ion of persistent pathological pain. Cortistatin - 14, which is involved in sleep regulation, locomotor activity, and cortical function, seems to be a high potency ligand at this receptor. Also, the multifunctional antibacterial protein LL - 37 has been shown to activate cells presumably through MRGPRX2.
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UniProt
- Q96LB1
抗原
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