Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
MRGPRX2 or cortistatin receptor is a 330 amino acid protein that belongs to the G - protein coupled receptor 1 family. Mas - related G - protein - coupled receptors (Mrgprs) represent a large family of orphan receptors specifically expressed in small - diameter nociceptive primary sensory neurons. Physiological functions include mediation of itch or regulat ion of persistent pathological pain. Cortistatin - 14, which is involved in sleep regulation, locomotor activity, and cortical function, seems to be a high potency ligand at this receptor. Also, the multifunctional antibacterial protein LL - 37 has been shown to activate cells presumably through MRGPRX2.