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ICAM-3/CD50 抗体

The 小鼠 单克隆 anti-ICAM-3/CD50 antibody is suitable to detect ICAM-3/CD50 in samples from 人. It has been validated for FACS, WB, IF, IP, ICC, IHC (fro) 和 EIA.
产品编号 ABIN5540802
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ICAM-3/CD50 抗体 (ABIN5540802)

抗原

See all ICAM-3/CD50 (ICAM3) 抗体
ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ICAM-3/CD50 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

MA4
  • 特异性

    This MA4 antibody recognizes a linear epitope in domains 1 and 2 of ICAM-3. MA4 robustly inhibits apoptotic cell interaction with phagocytes.

    纯化方法

    Purified

    免疫原

    Derived by fusion of mouse Ag8.653 cells with spleen cells from a BALB/c mouse immunized with an ICAM-3/HEK transfectant.

    亚型

    IgG1
  • 应用备注

    ELISA. Western Blot. Immunoprecipitation. Flow Cytometry. Immunocytochemistry. Immunohistochemistry on Frozen Sections. Recommended Dilutions: 1/100-1/200 for Flow Cytometry, and for Immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1/100-1/1000 for Immunoblotting applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer System: PBS Preservatives: 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

    别名

    cd50,icam3

    背景

    Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a type I transmembrane glycoprotein, which normally contain 2-9 immunoglobulin-like C2-type domains, and binds to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM-3 has previously been implicated in apoptotic cell clearance, although its precise role in the clearance process is ill defined.

    UniProt

    P32942
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