ICT1 抗体 (AA 30-206)
Quick Overview for ICT1 抗体 (AA 30-206) (ABIN5540729)
抗原
See all ICT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 30-206
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特异性
- This antibody detects ICT1 at aa30-206.
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纯化方法
- Protein-A affinity chromatography
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免疫原
- Recombinant human ICT1 (30-206aa) purified from E. coli
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亚型
- IgG1
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anti-Immature Colon Carcinoma Transcript 1 (ICT1) (AA 107-206) antibody
ICT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F8 unconjugated
anti-Immature Colon Carcinoma Transcript 1 (ICT1) (AA 1-206) antibodyICT1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Immature Colon Carcinoma Transcript 1 (ICT1) (AA 153-179), (C-Term) antibodyICT1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB42881 unconjugated
anti-Immature Colon Carcinoma Transcript 1 (ICT1) (AA 1-206) antibodyICT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Immature Colon Carcinoma Transcript 1 (ICT1) (AA 107-206) antibodyICT1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4C10 unconjugated
anti-Immature Colon Carcinoma Transcript 1 (ICT1) (AA 108-157) antibodyICT1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Immature Colon Carcinoma Transcript 1 (ICT1) (AA 30-206) antibodyICT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA. Western blot: Recommended starting dilution is 1:1000. Flow cytometry.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))
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别名
- ict1,ds1
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背景
- Peptidyl-tRNA hydrolase ICT1 acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. This neoplastic-induced deviation is marked by a change in expression of several mRNAs. ICT1 is a member of the prokaryotic/mitochondrial release factor family whose expression is downregulated over 4 fold upon colon stem cell differentiation. This downregulation of ICT1 could lead to its use as a marker for detection of colon carcinomas.
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UniProt
- Q14197
抗原
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