HINT2 抗体 (AA 18-163)
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Quick Overview for HINT2 抗体 (AA 18-163) (ABIN5540727)
抗原
See all HINT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 18-163
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纯化方法
- Protein-A affinity chromatography
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免疫原
- Recombinant human HINT2 (18-163aa) purified from E. coli.
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亚型
- IgG1
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应用备注
- The antibody has been tested by ELISA, Western blot analysis and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- HINT2 (Histidine Triad Nucleotide Binding Protein 2 (HINT2))
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别名
- hint2
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背景
- Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression. This protein is a member of the HIT superfamily and Hint subfamily, which are characterized as nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides. HINT2 regulates steroidogenesis through calcium-dependent and calcium-independent siglling pathways that may serve to maintain a favorable mitochondrial potential. Its role in calcium homeostasis may also contribute to its proapoptotic function in hepatocytes and other non-steroidogenic cells, though the exact mechanism remains unclear.
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UniProt
- Q9BX68
抗原
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