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HINT2 抗体 (AA 18-163)

This anti-HINT2 antibody is a 小鼠 单克隆 antibody detecting HINT2 in WB, FACS 和 EIA. Suitable for 人.
产品编号 ABIN5540727
发货至: 中国

Quick Overview for HINT2 抗体 (AA 18-163) (ABIN5540727)

抗原

See all HINT2 抗体
HINT2 (Histidine Triad Nucleotide Binding Protein 2 (HINT2))

适用

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宿主

  • 17
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小鼠

克隆类型

  • 18
  • 3
单克隆

标记

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This HINT2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

克隆位点

AT5B10
  • 抗原表位

    • 2
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    • 1
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    AA 18-163

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Recombinant human HINT2 (18-163aa) purified from E. coli.

    亚型

    IgG1
  • 应用备注

    The antibody has been tested by ELISA, Western blot analysis and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    HINT2 (Histidine Triad Nucleotide Binding Protein 2 (HINT2))

    别名

    hint2

    背景

    Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression. This protein is a member of the HIT superfamily and Hint subfamily, which are characterized as nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides. HINT2 regulates steroidogenesis through calcium-dependent and calcium-independent siglling pathways that may serve to maintain a favorable mitochondrial potential. Its role in calcium homeostasis may also contribute to its proapoptotic function in hepatocytes and other non-steroidogenic cells, though the exact mechanism remains unclear.

    UniProt

    Q9BX68
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