Syndecan 2 抗体
Quick Overview for Syndecan 2 抗体 (ABIN5540684)
抗原
See all Syndecan 2 (SDC2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This Monoclonal antibody is specific for a core protein epitope of a Human small basement membrane Heparan Sulfate Proteoglycan (HS-PG). AM20231PU recognizes an epitope different from that recognized by clones 1F10/B8 (Cat.No AM02102PU) and 2H7/G11 (Cat.-No AM02103PU). Species: Human.
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纯化方法
- Protein G Chromatography
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免疫原
- Purified Human small basement membrane Heparan Sulfate Proteoglycan (HS-PG)
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亚型
- IgG1
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anti-Syndecan 2 (SDC2) (C-Term) antibody
SDC2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Syndecan 2 (SDC2) (AA 32-130) antibodySDC2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-Syndecan 2 (SDC2) (AA 19-201) antibodySDC2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Syndecan 2 (SDC2) antibodySDC2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA (less than 1 μg/mL). Western blot (1 μg/mL). Immunohistochemistry (1 μg/mL)
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限制
- 仅限研究用
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缓冲液
- 50 mM TRIS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- Syndecan 2 (SDC2)
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别名
- hspg1,syndecan-2
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背景
- The principal molecular structure of basement membranes has been elucidated during the past two decades and it was shown that for example in the glomerular basement membrane (GBM) HS-PG are responsible for the selective filtration process. Removal of HS-PG will lead to proteinuria. Whereas previously perlecan was the only known basement membrane HS-PG, there is now evidence that (at least two) other basement membrane HS-PG do exist: Agrin, originally discovered as an important component of the neuromuscular junction and a novel small HS-PG, that was isolated from human aorta and kidney. This HS-PG, with a molecular weight of 80-200 kDa (aorta) and 30-160 kDa (kidney) and a core protein size of 24 kDa or 22 kDa, respectively, was localized by immunohistoche-mistry to the basement membrane. Amino acid sequence ana-lysis of tryptic peptides indicate, that this small HS-PG is clearly distinct from perlecan and agrin.
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UniProt
- P34741
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途径
- Glycosaminoglycan Metabolic Process
抗原
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