SPTAN1 抗体
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北京 101111
Quick Overview for SPTAN1 抗体 (ABIN5540660)
抗原
See all SPTAN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Specific for the ~240 k alpha II Spectrin protein.
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纯化方法
- Affinity Chromatography
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免疫原
- Recombinant construct containing the seventh, eighth and ninth repeats of human alpha II spectrin expressed in and purified from E. Coli.
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亚型
- IgG1
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应用备注
- Western Blot: 1/3000. Immunofluorescence: 1/500.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS Preservatives: 10 mM Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
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别名
- spectrin alpha chain (brain),sptan1
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背景
- The spectrin family of cytoskeletal proteins is comprised of 2 alpha genes (α1 and α2) and five beta genes (β1-β5). Spectrins have been shown to function as scaffolding proteins in mechanical support of the plasma membrane as well as bind other membrane proteins and lipids (Bennett and Baines 2001). Defects in spectrin genes have been linked to some forms of hereditary spherocytosis, a type of auto-hemolytic anemia which is characterized by spherical red blood cells that are more prone to lysis (Eber and Lux 2004).
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UniProt
- P07751
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途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization
抗原
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