RanBP3 抗体 (AA 235-445)
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Quick Overview for RanBP3 抗体 (AA 235-445) (ABIN5540644)
抗原
See all RanBP3 (RANBP3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 235-445
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特异性
- Recognizes Human RANBP3. Other species not tested.
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纯化方法
- Protein-A affinity chromatography
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免疫原
- Recombinant human RANBP3 (235-445aa) purified from E. coli.
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亚型
- IgG1
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应用备注
- The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))
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别名
- ranbp3
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背景
- The GTPase Ran is a small protein that belongs to the RAS protein superfamily and is found associated with the nuclear membrane. Ran GTPase is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. Ran binding proteins (RanBPs) belong to a family of proteins that bind Ran GTPase and help to stimulate its GTPase activity. Members of the RanBP family show weak similarity to importin beta, a protein involved in the transport of proteins to the nuclear membrane. Recently it has been shown that RanBP3 function is regulated by the Ras/ERK/RSK and PI3K/Akt signaling pathway. This finding has provided a link between nuclear transport, cell signaling, and cell fate.
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UniProt
- Q9H6Z4
抗原
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