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RanBP3 抗体 (AA 235-445)

The 小鼠 单克隆 anti-RanBP3 antibody (Clone AT12E11) (ABIN5540644) specifically detects RanBP3 in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN5540644
发货至: 中国
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Quick Overview for RanBP3 抗体 (AA 235-445) (ABIN5540644)

抗原

See all RanBP3 (RANBP3) 抗体
RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This RanBP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

AT12E11
  • 抗原表位

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    AA 235-445

    特异性

    Recognizes Human RANBP3. Other species not tested.

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Recombinant human RANBP3 (235-445aa) purified from E. coli.

    亚型

    IgG1
  • 应用备注

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

    别名

    ranbp3

    背景

    The GTPase Ran is a small protein that belongs to the RAS protein superfamily and is found associated with the nuclear membrane. Ran GTPase is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. Ran binding proteins (RanBPs) belong to a family of proteins that bind Ran GTPase and help to stimulate its GTPase activity. Members of the RanBP family show weak similarity to importin beta, a protein involved in the transport of proteins to the nuclear membrane. Recently it has been shown that RanBP3 function is regulated by the Ras/ERK/RSK and PI3K/Akt signaling pathway. This finding has provided a link between nuclear transport, cell signaling, and cell fate.

    UniProt

    Q9H6Z4
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