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PTPRT 抗体 (AA 1-742)

This 小鼠 单克隆 anti-PTPRT antibody (Clone 3D7) specifically detects PTPRT in WB, FACS, ICC, IF 和 IP. The antibody is reactive with 人, 大鼠 和 Pig samples.
产品编号 ABIN5540588
发货至: 中国
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Quick Overview for PTPRT 抗体 (AA 1-742) (ABIN5540588)

抗原

See all PTPRT 抗体
PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

适用

  • 12
  • 12
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, Pig

宿主

  • 12
小鼠

克隆类型

  • 12
单克隆

标记

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PTPRT antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

3D7
  • 抗原表位

    • 2
    • 1
    • 1
    AA 1-742

    特异性

    Monoclonal antibodies 3G4 and 3D7 have been directed against the extracellular domain of RPTPμ.

    纯化方法

    Purified

    免疫原

    This antibody has been derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with ExG protein, secreted by NIH-3T3 transfected cells and purified with glutahione beads. The cells have been transfected using a fusion construct, termed ExG, encoding the entire ectodomain of the Human RPTPmu molecule (aa 1-742), fused COOH terminally to GST.

    亚型

    IgG2a
  • 应用备注

    Western blot. Immunoprecipitation. Immunofluorescence. Flow Cytometry.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer System: PBS Preservatives: 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

    别名

    ptprt

    背景

    Receptor-like protein tyrosine phosphatases (RPTPs) represent a new family of transmembrane proteins that are thought to transduce external signals by dephosphorylating phosphotyrosine residues on intracellular substrates. RPTPμ is a prototypic receptor-like protein-tyrosine phosphatase (RPTP) that mediates homotypic cell-cell interactions. Intracellularly, RPTPμ consists of a relatively large juxtamembrane region (about 150 amino acids) and two conserved phosphatase domains. As in most RPTPs, the first (membrane-proximal) PTP domain of RPTPμ is catalytically active, whereas its second (C-terminal) domain is inactive. RPTPμ is involved in cell-cell adhesion through homophilic interactions and may also play a key role in signal transduction and growth control.

    UniProt

    O14522
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