Layilin 抗体 (AA 22-235)
Quick Overview for Layilin 抗体 (AA 22-235) (ABIN5540461)
抗原
See all Layilin (LAYN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 22-235
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纯化方法
- Protein-A affinity chromatography
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免疫原
- Recombinant human LAYN (22-235aa) purified from E. coli
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亚型
- IgG2b
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anti-Layilin (LAYN) (Internal Region) antibody
LAYN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Layilin (LAYN) (AA 281-382) antibodyLAYN 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Layilin (LAYN) (AA 1-374) antibodyLAYN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Layilin (LAYN) (Internal Region) antibodyLAYN 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Layilin (LAYN) (AA 262-382) antibodyLAYN 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Layilin (LAYN) (AA 22-235) antibodyLAYN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT18E10 unconjugated
anti-Layilin (LAYN) (AA 41-90) antibodyLAYN 适用: 人, 小鼠, 大鼠, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Layilin (LAYN) (N-Term) antibodyLAYN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Layilin (LAYN) (Internal Region) antibodyLAYN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- Layilin (LAYN)
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别名
- layilin
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背景
- Layilin is a widely expressed integral membrane hyaluronan receptor and a transmembrane protein with homology to C-type lectins. This protein interacts with the ERM protein family of cytoskeletal membrane linker molecule members, including talin, ezrin, moesin, and radixin. The carboxy-terminal domain of layilin is capable of binding to the amino-terminal domain of radixin. An interdomain interaction between the amino- and the carboxy-terminal domains of radixin inhibits its ability to bind to layilin. Layilin plays an important role in cell adhesion and motility. It is important for the maintenance of the cortical structure in the cell because it mediates signals from the extracellular matrix to the cytoskeleton. In spreading cells, Layilin acts as a membrane-binding site for talin in the peripheral ruffles, and it may play a role in the migration of cells to a wound site.
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UniProt
- Q6UX15
抗原
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