ELISA: Dilute the antibody approx. 1:300,000 for detection of Kchip1 peptide (QTKQRRPSKDK) coated on ELISA plate. Western blot: Dilute approx. 1:4,000 to detect the 27 kDa Kchip1 in mouse brain extract.
限制
仅限研究用
缓冲液
0.01M PBS, pH 7.4
储存液
Azide free
储存条件
4 °C,-20 °C
储存方法
Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
有效期
12 months
抗原
KCNIP1
(Kv Channel Interacting Protein 1 (KCNIP1))
别名
kcnip1,vabp
背景
KChIP1 is an important member of the potassium channel interacting protein family. It binds to and influences the voltage gated potassium (Kv) channel. Like all other members in the family, KChIP1 has calcium binding domains (EF-hand-like) that sense calcium concentrations to regulate Kv channel. KChIP1 frequently forms complex with the rapid inactivating A-type Kv channels. It may play a role in modulating somatodendritic excitability, and the repolarization of cardiac myocytes following action potential. It is also reported that KChIP1 is associated with the GABAergic synapses in hippocampus.