KCNIP1 抗体 (AA 12-22)
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Quick Overview for KCNIP1 抗体 (AA 12-22) (ABIN5540452)
抗原
See all KCNIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-22
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序列
- QTKQRRPSKD K
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特异性
- This antibody is reactive to the 27 kDa Kchip1 in Mouse and other species with consensus Kchip1 sequence.
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纯化方法
- Protein G affinity
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免疫原
- A synthetic peptide derived from the amino sequence amino acid 12-22 of mouse Kchip1, conjugated with KLH
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应用备注
- ELISA: Dilute the antibody approx. 1:300,000 for detection of Kchip1 peptide (QTKQRRPSKDK) coated on ELISA plate. Western blot: Dilute approx. 1:4,000 to detect the 27 kDa Kchip1 in mouse brain extract.
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限制
- 仅限研究用
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缓冲液
- 0.01M PBS, pH 7.4
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- KCNIP1 (Kv Channel Interacting Protein 1 (KCNIP1))
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别名
- kcnip1,vabp
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背景
- KChIP1 is an important member of the potassium channel interacting protein family. It binds to and influences the voltage gated potassium (Kv) channel. Like all other members in the family, KChIP1 has calcium binding domains (EF-hand-like) that sense calcium concentrations to regulate Kv channel. KChIP1 frequently forms complex with the rapid inactivating A-type Kv channels. It may play a role in modulating somatodendritic excitability, and the repolarization of cardiac myocytes following action potential. It is also reported that KChIP1 is associated with the GABAergic synapses in hippocampus.
抗原
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