GARS 抗体 (AA 43-289)
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Quick Overview for GARS 抗体 (AA 43-289) (ABIN5540351)
抗原
See all GARS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 43-289
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纯化方法
- Protein-A affinity chromatography
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免疫原
- Recombinant human GARS (43-289aa) purified from E. coli.
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亚型
- IgG1
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应用备注
- The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- GARS (Glycyl-tRNA Synthetase (GARS))
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别名
- glycyl-trna synthetase
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背景
- GARS, also known as glycyl-tRNA synthetase, is one of the aminoacyl-tRNA synthetase that charge tRNAs with their cognate amino acids. Defects in the gene encoding GlyRS is the cause of Charcot-Marie-Tooth disease type 2D (CMT2D), which is an autosomal dominant inherited disease characterized by severe weakness, atrophy and absence of deep tendon reflexes in the upper extremities. Defects in the GlyRS gene is also the cause of distal hereditary muscular neuropathy type V (HMN5), a disease similar to CMT2D, though the distal sensory involvement is less severe in HMN5 patients.
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UniProt
- P41250
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途径
- Ribonucleoside Biosynthetic Process
抗原
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