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FPR2 抗体 (2nd Extracellular Loop)

This anti-FPR2 antibody is a 兔 多克隆 antibody detecting FPR2 in WB, FACS, IF 和 ICC. Suitable for 人.
产品编号 ABIN5540339
发货至: 中国

Quick Overview for FPR2 抗体 (2nd Extracellular Loop) (ABIN5540339)

抗原

See all FPR2 抗体
FPR2 (Formyl Peptide Receptor 2 (FPR2))

适用

  • 50
  • 17
  • 16

宿主

  • 39
  • 10
  • 1

克隆类型

  • 41
  • 9
多克隆

标记

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  • 1
  • 1
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This FPR2 antibody is un-conjugated

应用范围

  • 32
  • 16
  • 13
  • 13
  • 7
  • 5
  • 5
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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 16
    • 5
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    2nd Extracellular Loop

    序列

    ASWGGTPEER LKC

    特异性

    This antibody recognizes a 38 kDa Human FPRL-1.

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    A short peptide corresponding to the amino acids on the 2nd extracellular loop of Human FPRL1
  • 应用备注

    Western blot: 1/4000-1/5000. Immunofluorescence: 1/400-1/500. Flow Cytometry: 1/100 using HL-60 as positive control .

    限制

    仅限研究用
  • 缓冲液

    0.01M PBS, pH 7.2

    储存条件

    4 °C,-20 °C

    储存方法

    Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    FPR2 (Formyl Peptide Receptor 2 (FPR2))

    别名

    fpr2,fprl1

    背景

    Human formyl peptide receptor-like 1(FPRL1) is a G-protein coupled seven transmembrane receptor. The receptor can bind to the formyl peptides derived from the degradation of the cell wall of infected bacteria and host cells. FPRL1 expressed on the cell surface of neutrophils and other leukocytes mediates the chemotaxis of these cells toward infected site. It has been reported that acute phase protein SAA is also a ligand of FPRL1 and SAA can induce the secretion of IL-8 and TNF-α by neutrophil through FPRL1 signalling. FPRL1 has also been shown to mediate the chemotaxis of microglia by Abeta42 peptide and the internalization of Abeta42 peptide into cytoplasma of macrophage, indicating that FRPL1 may participate in the Abeta42 peptide elicited pathogenesis in Alzheimer's disease.
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