AGPS 抗体 (AA 158-384)
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北京 101111
Quick Overview for AGPS 抗体 (AA 158-384) (ABIN5540330)
抗原
See all AGPS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 158-384
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特异性
- This antibody recognizes AGPS (alkykglycerone phosphate synthase), an peroxisomal enzyme important for lipid biosynthesis.
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纯化方法
- Protein-A affinity chromatography (>95% pure by SDS-PAGE)
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免疫原
- Recombinant human AGPS (amino acids 158-384)
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亚型
- IgG2a
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应用备注
- Flow cytometry. Western blot.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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有效期
- 12 months
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- AGPS (Alkylglycerone Phosphate Synthase (AGPS))
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别名
- agps,aag5
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背景
- AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.
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UniProt
- O00116
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途径
- SARS-CoV-2 Protein Interactome
抗原
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