EMCN
适用: 人, 小鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
应用备注
Western blot: 1-5 μg/mL. Immunofluorescence/ Immunohistochemistry: 1-5 μg/mL (Cryo).
限制
仅限研究用
缓冲液
PBS
储存条件
4 °C,-20 °C
储存方法
Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
有效期
12 months
抗原
Endomucin (EMCN)
别名
endomucin
背景
Endomucin (endothelial sialomucin also Endomucin-1/2 and Mucin-14) is an 80 - 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or anti-adhesive molecule. Mouse Endomucin precursor is 261 amino acids in length. It is type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa 21 - 190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD. One shows a deletion of aa 91 - 141, a second shows a one aa substitution for aa 91 - 129, and a third shows a one aa substitution for aa 129 - 142. Over aa 21 - 90, mouse Endomucin shares 60 % and 30 % aa identity with rat and human Endomucin, respectively.