Endomucin 抗体 (AA 20-190)
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Quick Overview for Endomucin 抗体 (AA 20-190) (ABIN5540322)
抗原
See all Endomucin (EMCN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-190
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特异性
- This antibody detects Mouse Endomucin (Glu20-Ser190). Other species not tested.
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纯化方法
- Protein A Chromatography
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免疫原
- Highly pure (> 95%) recombinant Mouse soluble Endomucin (Glu20-Ser190) derived from E. coli (Cat.-No. AR60010PU-N)
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亚型
- IgG
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应用备注
- Western blot: 1-5 μg/mL. FACS: 1-5 μg/mL.
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限制
- 仅限研究用
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缓冲液
- PBS
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- Endomucin (EMCN)
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别名
- endomucin
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背景
- Endomucin (endothelial sialomucin also Endomucin-1/2 and Mucin-14) is an 80 - 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or anti-adhesive molecule. Mouse Endomucin precursor is 261 amino acids in length. It is type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa 21 - 190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD. One shows a deletion of aa 91 - 141, a second shows a one aa substitution for aa 91 - 129, and a third shows a one aa substitution for aa 129 - 142. Over aa 21 - 90, mouse Endomucin shares 60 % and 30 % aa identity with rat and human Endomucin, respectively.
抗原
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