Cytokeratin 1 抗体 (pan) (FITC)
Quick Overview for Cytokeratin 1 抗体 (pan) (FITC) (ABIN5540281)
抗原
See all Cytokeratin 1 (KRT1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pan
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特异性
- AE 1/AE3 represents an excellent marker for distinguishing carcinomas from non-epithelial tumors reacts with all epithelium-derived tumors and their neoplasms. Decorates the majority of type I and type II keratins (formerly also designated cytokeratins). This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas. This antibody AE 1/AE 3 recognizes Low Molecular Weight Cytokeratins (CK 10 (56.5), CK14 (50), CK15 (50), CK16 (48) and CK19 (40) of the acidic family and CK1 (67), CK2 (65.5), CK3 (64), CK4 (59), CK5 (58) CK6 (56) and CK8 (52.5).
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纯化方法
- Protein A Chromatography
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免疫原
- Human epidermal keratin.
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亚型
- IgG1
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应用备注
- Immunofluorescence: 10-20 μg /mL (1/10-1/20), incubate for 2 hours in the dark at RT or it can also be incubated overnight at 4 °C. Flow Cytometry: 0.2-1.0 μg/0.1 mL (1/200-1/1,000) (Not tested in our lab).
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限制
- 仅限研究用
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状态
- Liquid
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
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- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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别名
- cytokeratin
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背景
- Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1(67), CK2(65.5), CK3(64), CK4(59), CK5(58), CK6(56), CK7(54), CK8(52.5) and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10 (56.5), CK12 (56), CK13 (53), CK14 (50), CK16 (48), CK17 (46), CK18 (45), CK19 (48) and CK20 (46).
抗原
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