CX3CR1 抗体
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北京 101111
Quick Overview for CX3CR1 抗体 (ABIN5540227)
抗原
See all CX3CR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detetcs CX3C Receptor 1. The specificity of the antibody was verified by flow cytometry with cells expressing the recombinant protein. The epitope has not been further characterized.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- DNA vaccine
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亚型
- IgG2b
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应用备注
- Immunohistochemistry on Paraffin Sections: 2 μg/mL (1/100), pretreatment with proteinase K required. Suggested Positive Control: Human brain cortex.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL BSA
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
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别名
- cx3cr1,gpr13
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背景
- G-protein coupled receptor 1 3 (GPR13) is a 355 amino acid protein that belongs to the G - protein coupled receptor 1 family. Biologically, the fractalkine (CX3CL1) to fractalkine receptor (CX3CR1) interactions play an important role in macrophage recruitment to target organs such as the brain, the intestine, the liver or the lungs. Accordingly, expression of the CX3CR1 has been described in inflammation - and tumor - associated macrophages, intestinal lamina propia macrophages, and B cells. Also, CX3CR1 mediates adhesive and migratory functions and acts as a coreceptor with CD4 for HIV - 1 virus gp160 envelope protein.
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UniProt
- P49238
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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