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Cathepsin S 抗体 (AA 17-331)

This anti-Cathepsin S antibody is a 小鼠 单克隆 antibody detecting Cathepsin S in WB 和 EIA. Suitable for 人.
产品编号 ABIN5540225
发货至: 中国

Quick Overview for Cathepsin S 抗体 (AA 17-331) (ABIN5540225)

抗原

See all Cathepsin S (CTSS) 抗体
Cathepsin S (CTSS)

适用

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宿主

  • 66
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小鼠

克隆类型

  • 64
  • 15
单克隆

标记

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This Cathepsin S antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

AT1F9
  • 抗原表位

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    AA 17-331

    特异性

    This antibofy recognizes Human CTSS. Other species not tested.

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Recombinant human CTSS (17-331aa) purified from E. coli

    亚型

    IgG2b
  • 应用备注

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution: 1/500.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Cathepsin S (CTSS)

    别名

    cathepsin s

    背景

    CTSS (Cathepsin S) is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, CTSS is expressed in some epithelial cells. In contrast, cortical thymic epithelial cells do not express CTSS. Normal epidermal keratinocytes do not express CTSS. However, level of CTSS is elevated in psoriatic keratinocytes due to stimulation by proinflammatory factors. CTSS can function as an elastase over a broad pH range in alveolar macrophages.

    UniProt

    P25774

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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