Cathepsin S 抗体 (AA 17-331)
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Quick Overview for Cathepsin S 抗体 (AA 17-331) (ABIN5540225)
抗原
See all Cathepsin S (CTSS) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 17-331
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特异性
- This antibofy recognizes Human CTSS. Other species not tested.
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Recombinant human CTSS (17-331aa) purified from E. coli
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亚型
- IgG2b
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应用备注
- The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution: 1/500.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- Cathepsin S (CTSS)
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别名
- cathepsin s
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背景
- CTSS (Cathepsin S) is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, CTSS is expressed in some epithelial cells. In contrast, cortical thymic epithelial cells do not express CTSS. Normal epidermal keratinocytes do not express CTSS. However, level of CTSS is elevated in psoriatic keratinocytes due to stimulation by proinflammatory factors. CTSS can function as an elastase over a broad pH range in alveolar macrophages.
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UniProt
- P25774
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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