Chromogranin A 抗体
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北京 101111
Quick Overview for Chromogranin A 抗体 (ABIN5540207)
抗原
See all Chromogranin A (CHGA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes Chromogranin A (CGA).
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Genetic immunisation with cDNA encoding CGA
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亚型
- IgG1
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应用备注
- Flow cytometry: 1.2 μg/10e6 cells. ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered saline, pH 7.2
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- Chromogranin A (CHGA)
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别名
- chromogranin a
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背景
- Chromogranin A (CgA) is a 49 kDa protein which is a member of the granin/secretogranin family of acidic glycoproteins. It is specifically expressed in all endocrine and neuroendocrine cells and plays multiple roles in the process of regulated secretion of peptide hormones and neurotransmitters (1). Owing to its over-expression in several tumors of neuroendocrine origin, CgA is of diagnostic value in classical endocrine, in hormone-negative and in neuroendocrine tumors (2).
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UniProt
- P10645
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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