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GAP43 抗体 (C-Term)

This 小鸡 多克隆 anti-GAP43 antibody specifically detects GAP43 in WB, IF 和 ICC. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN5540032
发货至: 中国
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Quick Overview for GAP43 抗体 (C-Term) (ABIN5540032)

抗原

See all GAP43 抗体
GAP43 (Growth Associated Protein 43 (GAP43))

适用

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人, 大鼠, 小鼠

宿主

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小鸡

克隆类型

  • 99
  • 51
多克隆

标记

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This GAP43 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects GAP43.

    纯化方法

    Ig Fraction

    免疫原

    Synthetic peptide corresponding to amino acid residues from the C-terminal region of the rat GAP43 sequence
  • 应用备注

    Western blot: 1/2000. Immunoflourescence: 1/500.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer System: PBS Preservatives: 10 mM Sodium azide

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    GAP43 (Growth Associated Protein 43 (GAP43))

    别名

    gap43

    背景

    GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration (Benowitz and Routtenberg, 1997). There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone (Strittmatter et al., 1995). GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser 41 by protein kinase C modulates the interaction of GAP-43 with actin (He et al., 1997) and may also affect neurotransmitter release during forms of plasticity like LTP (Hulo et al., 2002).

    UniProt

    P07936
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