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Aminoacylase 1 抗体 (AA 1-408)

This anti-Aminoacylase 1 antibody is a 小鼠 单克隆 antibody detecting Aminoacylase 1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN5539999
发货至: 中国

Quick Overview for Aminoacylase 1 抗体 (AA 1-408) (ABIN5539999)

抗原

See all Aminoacylase 1 (ACY1) 抗体
Aminoacylase 1 (ACY1)

适用

  • 34
  • 14
  • 4
  • 2
  • 1
  • 1

宿主

  • 23
  • 12
  • 2
小鼠

克隆类型

  • 25
  • 12
单克隆

标记

  • 30
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aminoacylase 1 antibody is un-conjugated

应用范围

  • 28
  • 15
  • 14
  • 7
  • 7
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

AT1E2
  • 抗原表位

    • 9
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-408

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Recombinant human ACY1 (1-408aa) purified from E. coli.

    亚型

    IgG2b
  • 应用备注

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Aminoacylase 1 (ACY1)

    别名

    aminoacylase-1,acy1

    背景

    Aminoacylase-1, also designated N-acyl-L-amino-acid amidohydrolase or ACY1, is a member of the largest metallopeptidase family called M20A. Aminoacylase-1 is a zinc-binding homodimeric enzyme expressed in kidney, brain, placenta and spleen. It is the most abundant of the aminoacylases. Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D). ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. All affected individuals exhibit markedly increased urinary excretion of several N-acetylated amino acids.

    UniProt

    Q03154
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