ACPP 抗体
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北京 101111
Quick Overview for ACPP 抗体 (ABIN5539951)
抗原
See all ACPP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes Prostatic Acid Phosphatase PAP (PAcP, ACPP).
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Genetic immunisation with cDNA encoding Human PAP.
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亚型
- IgG1
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应用备注
- Flow cytometry: 1.2 μg/10e6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. ELISA (detection): With clone LT-6C11-A1 as capture antibody.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered saline, pH 7.2
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- ACPP (Acid Phosphatase, Prostate (ACPP))
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别名
- acpp,prostatic acid phosphatase
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背景
- Human prostatic acid phosphatase (PAP) is a non-specific phosphomonoesterase, synthesised and secreted into seminal plasma under androgenic control. Human PAP is a 100 kDa glycoprotein containing two subunits of approximately 50 kDa each (1,2). It catalyses the dephosphorylation of organic monophosphate esters, demonstrating optimum activity at an acid pH . Produced by the prostatic epithelium, serum levels of PAP are very low in healthy individuals, but are often elevated in malignant and benign prostatic disease while it has been used as a marker of diagnosis and therapy control of cancer of the prostate gland (3).
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UniProt
- P15309
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途径
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
抗原
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