IRS4 抗体 (AA 633-647)
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北京 101111
Quick Overview for IRS4 抗体 (AA 633-647) (ABIN5539610)
抗原
See all IRS4 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 633-647
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原理
- Irs4 (mouse aa633-647)
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序列
- DRGTKERKEA KEVRD
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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亚型
- IgG
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anti-Insulin Receptor Substrate 4 (IRS4) (AA 850-950) antibody
IRS4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B9 unconjugated
anti-Insulin Receptor Substrate 4 (IRS4) (AA 401-500) antibodyIRS4 适用: 小鼠, 大鼠 IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 4 (IRS4) (C-Term) antibodyIRS4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 4 (IRS4) (AA 1-196) antibodyIRS4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 4 (IRS4) (AA 1-299) antibodyIRS4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: Approx 150 kDa band observed in Mouse Heart lysates (calculated MW of 130 kDa according to NP_034702.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Schreyer et al, jEndocrinology. 20
Peptide ELISA: antibody detection limit dilution 1:128000.
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说明
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Immunofluorescence: This product has been successfully used in IF on Mouse: Harriet M Jackson et al, BMC Genomics. 2013 Nov 25,14:831. PMID: 24274089.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Minimize freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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: "IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation." in: Nature communications, Vol. 7, pp. 13567, (2018) (PubMed).
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: "IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation." in: Nature communications, Vol. 7, pp. 13567, (2018) (PubMed).
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- IRS4 (Insulin Receptor Substrate 4 (IRS4))
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别名
- Irs4
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背景
- Irs4, insulin receptor substrate 4, IRS-4, RP23-415G1.3, phosphoprotein of 160 kDa, pp160
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基因ID
- 16370, 315350
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NCBI登录号
- NP_034702
抗原
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