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HAT1 抗体 (N-Term)

This anti-HAT1 antibody is a 兔 多克隆 antibody detecting HAT1 in WB. Suitable for 人.
产品编号 ABIN5539371
发货至: 中国

Quick Overview for HAT1 抗体 (N-Term) (ABIN5539371)

抗原

See all HAT1 抗体
HAT1 (Histone Aminotransferase 1 (HAT1))

适用

宿主

  • 4

克隆类型

  • 4
多克隆

标记

  • 4
This HAT1 antibody is un-conjugated

应用范围

Western Blotting (WB)
  • 抗原表位

    • 2
    • 2
    • 1
    AA 27-58, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

    免疫原

    This KAT1 (HAT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-58 amino acids from the N-terminal region of human KAT1 (HAT1).

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    HAT1 (Histone Aminotransferase 1 (HAT1))

    别名

    KAT1

    背景

    Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.

    分子量

    50 kDa

    基因ID

    8520

    UniProt

    O14929
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